Beneficial Effects of Tocotrienol and Tocopherol on Bone Histomorphometric Parameters in Sprague–Dawley Male Rats After Nicotine Cessation

• Published in: Calcified tissue international Vol. 84; no. 1; pp. 65 - 74
• Main Authors: Hermizi, Hapidin, Faizah, Othman, Ima-Nirwana, Soelaiman, Ahmad Nazrun, Shuid, Norazlina, Mohamed
• Format: Journal Article
• Language: English
• Published: New York Springer-Verlag 2009; Springer Nature B.V
• Subjects: Animals; Biochemistry; Biomedical and Life Sciences; Bone and Bones - drug effects; Bone and Bones - physiology; Bone and Bones - ultrastructure; Bone density; Cell Biology; Chromans - pharmacology; Endocrinology; Life Sciences; Male; Nicotine; Nicotine - adverse effects; Nicotine - antagonists & inhibitors; Orthopedics; Osteogenesis - drug effects; Osteoporosis - chemically induced; Osteoporosis - prevention & control; Rats; Rats, Sprague-Dawley; Rodents; Smoking; Smoking - adverse effects; Tocopherols - pharmacology; Vitamin E; Vitamin E - analogs & derivatives; Vitamin E - pharmacology; Bone histomorphometry; Male rat; Vitamin E; Nicotine

This study was conducted to determine the effectiveness of three forms of vitamin E supplements following nicotine treatment on bone histomorphometric parameters in an adult male rat model. Rats were divided into seven groups: baseline (B, killed without treatment), control (C, normal saline for 4 m...