Relationship Between Amyloid Precursor Protein in Seminal Plasma and Abnormal Penile Sympathetic Skin Response in Lifelong Premature Ejaculation

• Published in: Journal of sexual medicine Vol. 14; no. 1; p. 98
• Main Authors: Hong, Zhiwei, Feng, Yuming, Ding, Hualong, Hu, Xuechun, Lu, Jin-Chun, Ge, Xie, Ge, Yifeng, Yao, Bing
• Format: Journal Article
• Language: English
• Published: Netherlands 01.01.2017
• Subjects: Adult; Andrology; Case-Control Studies; Ejaculation - physiology; Humans; Male; Penis - physiopathology; Premature Ejaculation - physiopathology; Semen; Skin - metabolism; Sympathetic Nervous System - metabolism; Young Adult; Penile Skin Sympathetic Response; Amyloid Precursor Protein; Seminal Plasma Protein; Amyloid-β; Premature Ejaculation

Hyperactivity of the sympathetic nervous system can play an important role in lifelong premature ejaculation (PE). Our previous study found that amyloid precursor protein (APP) levels in seminal plasma of patients with PE were clearly increased. Amyloid-β (Aβ) is derived from APP. Excessive Aβ, espe...