The role of leptin and adiponectin as mediators in the relationship between adiposity and hand and knee osteoarthritis

• Published in: Osteoarthritis and cartilage Vol. 27; no. 12; pp. 1761 - 1767
• Main Authors: Kroon, F.P.B., Veenbrink, A.I., de Mutsert, R., Visser, A.W., van Dijk, K.W., le Cessie, S., Rosendaal, F.R., Kloppenburg, M.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.12.2019
• Subjects: Adipokines; Mediation analysis; Obesity; Osteoarthritis; Obesity; Adipokines; Osteoarthritis; Mediation analysis

To investigate associations of leptin and adiponectin levels with knee and hand osteoarthritis, and explore whether these mediate the association between adiposity and osteoarthritis. This is a cross-sectional analysis of baseline data from the population-based Netherlands Epidemiology of Obesity st...