Overexpression of PSAT1 promotes metastasis of lung adenocarcinoma by suppressing the IRF1-IFNγ axis - Chan, Yung-Chieh; Chang, Yu-Chan; Chuang, Hsiang-Hao; Yang, Yi-Chieh; Lin, Yuan-Feng; Huang, Ming-Shyan; Hsiao, Michael; Yang, Chih-Jen; Hua, Kuo-Tai (Oncogene, 2020)
Keywords: 13/105; 38/61; 631/67/1612; 631/67/322; 64/60; Adenocarcinoma; Adenocarcinoma of Lung - enzymology; Adenocarcinoma of Lung - genetics; Adenocarcinoma of Lung - metabolism; Adenocarcinoma of Lung - pathology; Animals; Apoptosis; Cell Biology; Cohort Studies; Disease Progression; DNA microarrays; Gene expression; Gene Knockdown Techniques; Glutamine; Human Genetics; Humans; Immunohistochemistry; Interferon regulatory factor; Interferon regulatory factor 1; Interferon Regulatory Factor-1 - antagonists & inhibitors; Interferon Regulatory Factor-1 - metabolism; Interferon-gamma - antagonists & inhibitors; Interferon-gamma - metabolism; Internal Medicine; Lung cancer; Lung Neoplasms - enzymology; Lung Neoplasms - genetics; Lung Neoplasms - metabolism; Lung Neoplasms - pathology; Male; Medicine; Medicine & Public Health; Metastases; Metastasis; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Oncology; Phosphoserine; Phosphoserine aminotransferase; RNA, Messenger - metabolism; RNA, Neoplasm - metabolism; Serine; Signal Transduction; Therapeutic applications; Therapeutic targets; Tissue Array Analysis; Transaminases; Transcription; Up-Regulation; γ-Interferon