Safety, pharmacokinetics, and pharmacodynamics of TG103, a novel long-acting GLP-1/Fc fusion protein after a single ascending dose in Chinese healthy subjects - Jin, Jiangli; Cui, Gang; Mi, Na; Wu, Wei; Zhang, Xin; Xiao, Chunyan; Wang, Jing; Qiu, Xueying; Han, Mai; Li, Ziyan; Wang, Lei; Lu, Tong; et al. (European journal of pharmaceutical sciences, 2023)
Keywords: Area Under Curve; Blood Glucose; Diabetes Mellitus, Type 2 - drug therapy; Dose-Response Relationship, Drug; Double-Blind Method; East Asian People; Fc-fusion protein; Glucagon-Like Peptide 1; Half-Life; Healthy Volunteers; Humans; Oral glucose tolerance test; Pharmacodynamics; Pharmacokinetic; Safety; Type 2 diabetes millitus; Oral glucose tolerance test; Glucagon-like peptide-1; Pharmacodynamics; Type 2 diabetes millitus; Fc-fusion protein; Safety; Pharmacokinetic