Lectins as inducers of interferon-gamma production in human lymphocytes: lentil lectin is highly efficient

• Published in: Scandinavian journal of immunology Vol. 16; no. 4; p. 327
• Main Authors: Rönnblom, L, Funa, K, Ersson, B, Alm, G V
• Format: Journal Article
• Language: English
• Published: England 01.10.1982
• Subjects: Humans; In Vitro Techniques; Interferon Inducers; Interferon Type I - biosynthesis; Interferon-gamma - biosynthesis; Lectins - pharmacology; Lymphocytes - immunology; Macrophages - immunology; Plant Lectins; T-Lymphocytes - immunology

Several of many tested plant lectins induced interferon (IFN) production in cultures of human peripheral blood mononuclear leucocytes (PBL). The mannose-binding lectin obtained from Lens culinaris (LCL) was a particularly efficient inducer of trypsin-sensitive antiviral activity, which qualified as...