Microencapsulated tumor assay：Evaluation of the nude mouse model of pancreatic cancer

• Published in: World journal of gastroenterology : WJG Vol. 18; no. 3; pp. 257 - 267
• Main Author: Ma, Ming-Zhe
• Format: Journal Article
• Language: English
• Published: United States Baishideng Publishing Group Co., Limited 21.01.2012
• Subjects: Animals; Brief; Disease Models, Animal; Disease Progression; Drug Compounding; Female; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation - methods; Pancreatic Neoplasms - pathology; Tumor Burden; Tumor Cells, Cultured; 小鼠模型; 微球; 微胶囊技术; 正电子发射断层扫描; 肿瘤检测; 肿瘤细胞; 胰腺癌; 评价; Encapsulation; Model of pancreatic neoplasms; Orthotopic implantation model; Subcutaneous implantation model; Nude mice
• ISSN: 1007-9327; 2219-2840; 2219-2840
• DOI: 10.3748/wjg.v17.i3.257

AIM： To establish a more stable and accurate nude mouse model of pancreatic cancer using cancer cell microencapsulation. METHODS： The assay is based on microencapsulation technology, wherein human tumor cells are encapsulated in small microcapsules （approximately 420 μm in diameter） constructed of s...