Experimental recombining of repetitive motifs leads to large functional metallothioneins and demonstrates their modular evolvability potential - Dallinger, Reinhard; Pedrini‐Martha, Veronika; Burdisso, Maria Lucia; Capdevila, Mercè; Palacios, Oscar; Albalat, Ricard (Protein science, 2025)
Keywords: Amino Acid Motifs; Animals; artificial variants; Binding; Cadmium; Cadmium - chemistry; Cadmium - metabolism; domain repeat proteins; Evolution, Molecular; evolvability; Functional morphology; Functionals; gastropoda/mollusca MTs; Metallothionein - chemistry; Metallothionein - genetics; Metallothionein - metabolism; Metallothioneins; Models, Molecular; Modular structures; Modular systems; Modularity; Mollusks; Protein Domains; protein modularity; Protein structure; Proteins; Repetitive Sequences, Amino Acid; Sequences; snail Alinda biplicata; Snails - chemistry; Snails - genetics; Snails - metabolism; gastropoda/mollusca MTs; artificial variants; evolvability; protein modularity; domain repeat proteins; snail Alinda biplicata