Eosinophilic density in graft biopsies positive for rejection and blood eosinophil count can predict development of post-transplant digestive tract eosinophilia

• Published in: Pediatric transplantation Vol. 20; no. 4; pp. 540 - 551
• Main Authors: Bush, Jonathan W., Mohammad, Saeed, Melin-Aldana, Hector, Kagalwalla, Amir F., Arva, Nicoleta C.
• Format: Journal Article
• Language: English
• Published: Denmark Blackwell Publishing Ltd 01.06.2016
• Subjects: Biomarkers - metabolism; Biopsy; Child; Child, Preschool; Digestive System Diseases - diagnosis; Digestive System Diseases - etiology; Digestive System Diseases - immunology; Digestive System Diseases - pathology; Eosinophilia - diagnosis; Eosinophilia - etiology; Eosinophilia - immunology; Eosinophilia - pathology; Eosinophils - metabolism; Female; Follow-Up Studies; gastrointestinal eosinophilia; Graft Rejection - diagnosis; Graft Rejection - immunology; Graft Rejection - pathology; Humans; Kidney - immunology; Kidney - pathology; Leukocyte Count; Liver - immunology; Liver - pathology; Male; Myocardium - immunology; Myocardium - pathology; Organ Transplantation; Postoperative Complications - diagnosis; Postoperative Complications - immunology; Postoperative Complications - pathology; rejection; Retrospective Studies; transplant; Treatment Outcome; transplant; gastrointestinal eosinophilia; rejection

EGID is a known post‐transplant complication. Its etiology has been related to antirejection medication, but other factors may also play a role as only few transplant recipients develop EGID despite standardized treatment. This study aimed to determine whether EGID is associated with rejection event...