Feedback inhibition in the inner plexiform layer underlies the surround-mediated responses of AII amacrine cells in the mammalian retina

• Published in: The Journal of physiology Vol. 539; no. 2; pp. 603 - 614
• Main Authors: Völgyi, Béla, Xin, Daiyan, Bloomfield, Stewart A.
• Format: Journal Article
• Language: English
• Published: Oxford, UK The Physiological Society 01.03.2002; Blackwell Publishing Ltd; Blackwell Science Inc
• Subjects: Animals; Electrophysiology; Feedback - physiology; GABA Antagonists - pharmacology; GABA-A Receptor Antagonists; In Vitro Techniques; Nerve Net - cytology; Nerve Net - physiology; Original; Photic Stimulation; Presynaptic Terminals - drug effects; Presynaptic Terminals - physiology; Rabbits; Retina - cytology; Retina - physiology; Stilbenes - pharmacology; Visual Fields - physiology

Intracellular recordings were made from narrow-field, bistratified AII amacrine cells in the isolated, superfused retina-eyecup of the rabbit. Pharmacological agents were applied to neurons to dissect the synaptic pathways subserving AII cells so as to determine the circuitry generating their off-su...