Effect of ubiquitin on platelet functions: possible identity with platelet activity suppressive lymphokine (PASL)

• Published in: European journal of immunology Vol. 21; no. 11; p. 2735
• Main Authors: Pancré, V, Pierce, R J, Fournier, F, Mehtali, M, Delanoye, A, Capron, A, Auriault, C
• Format: Journal Article
• Language: English
• Published: Germany 01.11.1991
• Subjects: Adenosine Diphosphate - pharmacology; Amino Acid Sequence; Base Sequence; Bee Venoms - immunology; Blood Platelets - physiology; Cloning, Molecular; Cytotoxicity, Immunologic; Drug Hypersensitivity - immunology; Humans; Hypersensitivity - immunology; In Vitro Techniques; Luminescent Measurements; Lymphokines - physiology; Molecular Sequence Data; Platelet Activation - drug effects; Platelet Aggregation; Thrombin - pharmacology; Ubiquitins - physiology

In an attempt to clone a suppressive lymphokine of platelet function (PASL), we have obtained a cDNA clone coding for the previously described human ubiquitin-80 amino acid fusion protein. Our clone differs from the described sequence in that it contains the complete amino acid sequence of ubiquitin...