Impaired in vivo mitochondrial function but similar intramyocellular lipid content in patients with type 2 diabetes mellitus and BMI-matched control subjects - Schrauwen-Hinderling, V. B.; Kooi, M. E.; Hesselink, M. K. C.; Jeneson, J. A. L.; Backes, W. H.; van Echteld, C. J. A.; van Engelshoven, J. M. A.; Mensink, M.; Schrauwen, P. (Diabetologia, 2007)
Keywords: Aged; Biological and medical sciences; Blood Glucose - metabolism; Body Mass Index; Case-Control Studies; Diabetes; Diabetes Mellitus, Type 2 - metabolism; Diabetes Mellitus, Type 2 - physiopathology; Diabetes. Impaired glucose tolerance; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Etiology; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Fundamental and applied biological sciences. Psychology; Humans; Insulin - metabolism; Insulin resistance; Insulin Resistance - physiology; Lipid Metabolism - physiology; Lipids; Magnetic Resonance Spectroscopy; Male; Medical sciences; Medical screening; Metabolites; Middle Aged; Mitochondria, Muscle - physiology; Muscle, Skeletal - metabolism; Musculoskeletal system; Obesity; Obesity - metabolism; Obesity - physiopathology; Overweight; Phosphocreatine - metabolism; Phosphorus Isotopes; Spectrum analysis; Striated muscle. Tendons; Vertebrates: osteoarticular system, musculoskeletal system; Netherlands; Endocrinopathy; Type 2 diabetes; Human; Oxidative capacity; Metabolic diseases; Lipids; Striated muscle; Skeletal muscle; IMCL; Insulin resistance Lipid metabolism; In vivo; Mitochondria; Mitochondrial function; Insulin resistance; Diabetes