Modulating Hippocampal Plasticity with In Vivo Brain Stimulation

• Published in: The Journal of neuroscience Vol. 35; no. 37; pp. 12824 - 12832
• Main Authors: Rohan, Joyce G., Carhuatanta, Kim A., McInturf, Shawn M., Miklasevich, Molly K., Jankord, Ryan
• Format: Journal Article
• Language: English
• Published: United States Society for Neuroscience 16.09.2015
• Subjects: 2-Amino-5-phosphonovalerate - pharmacology; Animals; CA1 Region, Hippocampal - physiology; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists - pharmacology; Excitatory Postsynaptic Potentials - drug effects; Long-Term Potentiation - physiology; Male; Microelectrodes; Rats; Rats, Sprague-Dawley; brain stimulation; extracellular recording; long term potentiation; hippocampus; rat; tDCS

Investigations into the use of transcranial direct current stimulation (tDCS) in relieving symptoms of neurological disorders and enhancing cognitive or motor performance have exhibited promising results. However, the mechanisms by which tDCS effects brain function remain under scrutiny. We have dem...