Two zinc-aminoclays’ in-vitro cytotoxicity assessment in HeLa cells and in-vivo embryotoxicity assay in zebrafish

• Published in: Ecotoxicology and environmental safety Vol. 137; pp. 103 - 112
• Main Authors: Chun, Hang-Suk, Park, Duckshin, Eun Lim, Song, Jeong, Kwang-Hun, Park, Ji-Seon, Park, Han-Jin, Kang, Shinyoung, Kang, Kyoung Suk, Park, Hyun Gyu, An, Ha-Rim, Huh, Yun Suk, Lee, Young-Chul
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.03.2017
• Subjects: Animals; Cell Survival - drug effects; Cytotoxicity; Embryo, Nonmammalian - drug effects; Embryotoxicity; HeLa Cells; Humans; Metal Nanoparticles - chemistry; Metal Nanoparticles - toxicity; Propylamines - chemistry; Propylamines - toxicity; Reactive Oxygen Species - metabolism; Silanes - chemistry; Silanes - toxicity; Toxicity Tests; Zebrafish; Zebrafish - embryology; Zinc - chemistry; Zinc - toxicity; Zinc Compounds - chemistry; Zinc Compounds - toxicity; Zn-aminoclays; HeLa cells; Embryotoxicity; Cytotoxicity; Zebrafish; Zn-aminoclays

Two zinc-aminoclays [ZnACs] with functionalized primary amines [(-CH2)3NH2] were prepared by a simple sol-gel reaction using cationic metal precursors of ZnCl2 and Zn(NO3)2 with 3-aminopropyl triethoxysilane [APTES] under ambient conditions. Due to the facile interaction of heavy metals with primary...