Triple negative breast cancer: the kiss of death

• Published in: Oncotarget Vol. 8; no. 28; pp. 46652 - 46662
• Main Authors: Jitariu, Adriana-Andreea, Cîmpean, Anca Maria, Ribatti, Domenico, Raica, Marius
• Format: Journal Article
• Language: English
• Published: United States Impact Journals LLC 11.07.2017
• Subjects: Animals; Antineoplastic Agents - pharmacology; Antineoplastic Agents - therapeutic use; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Biomarkers, Tumor; Female; Humans; Molecular Targeted Therapy; Neoplasm Grading; Neoplasm Staging; Neovascularization, Pathologic; Receptor, ErbB-2 - genetics; Receptor, ErbB-2 - metabolism; Receptors, Estrogen - genetics; Receptors, Estrogen - metabolism; Receptors, Progesterone - genetics; Receptors, Progesterone - metabolism; Review; Treatment Outcome; Triple Negative Breast Neoplasms - diagnosis; Triple Negative Breast Neoplasms - etiology; Triple Negative Breast Neoplasms - metabolism; Triple Negative Breast Neoplasms - therapy; metastases; progression; triple negative breast cancer; therapeutic targets

One of the most controversial women malignancies, triple negative breast cancers (TNBCs) are critically overviewed here, being focused on data useful in clinical practice or to improve the therapy and patients survival. TNBCs "choose" young women and its "kiss" is, unfortunately...