Computational tools for aptamer identification and optimization - Sun, Di; Sun, Miao; Zhang, Jialu; Lin, Xin; Zhang, Yinkun; Lin, Fanghe; Zhang, Peng; Yang, Chaoyong; Song, Jia (TrAC, Trends in analytical chemistry (Regular ed.), 2022)
Keywords: analytical chemistry; Aptamer identification; Aptamer optimization; Bioinformatics; case studies; COVID-19; Deep learning; Machine learning; oligonucleotides; RNA; Severe acute respiratory syndrome coronavirus 2; single-stranded DNA; systematic evolution of ligands by exponential enrichment; AI; DL; SVM; Aptamer optimization; MFE; Deep learning; COVID-19; HT-SELEX; NLP; RF; Aptamer identification; Machine learning; MD; Bioinformatics; MDS; SELEX; ML