Risperidone versus haloperidol in children and adolescents with AD A randomized, controlled, double-blind trial

• Published in: European child & adolescent psychiatry Vol. 17; no. 1; pp. 1 - 8
• Main Authors: Miral, Suha, Gencer, Ozlem, Inal-Emiroglu, F. Neslihan, Baykara, Burak, Baykara, Aysen, Dirik, Eray
• Format: Journal Article
• Language: English
• Published: Dordrecht D. Steinkopff-Verlag 01.02.2008; Springer; Springer Nature B.V
• Subjects: Adolescent; Alanine Transaminase - blood; Antipsychotic Agents - adverse effects; Antipsychotic Agents - therapeutic use; Autistic Disorder - diagnosis; Autistic Disorder - drug therapy; Autistic Disorder - psychology; Biological and medical sciences; Child; Child and Adolescent Psychiatry; Child Behavior Disorders - diagnosis; Child Behavior Disorders - drug therapy; Child clinical studies; Developmental disorders; Dose-Response Relationship, Drug; Double-Blind Method; Dyskinesia, Drug-Induced - etiology; Female; Humans; Infantile autism; Male; Medical sciences; Medicine; Medicine & Public Health; Neuropharmacology; Original Contribution; Outcome Assessment (Health Care); Personality Assessment; Pharmacology. Drug treatments; Prolactin - blood; Psychiatry; Psycholeptics: tranquillizer, neuroleptic; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Psychopharmacology; Risperidone - adverse effects; Risperidone - therapeutic use; haloperidol; treatment; autistic disorder; risperidone; Human; Atypical antipsychotic; Psychotropic; Neuroleptic; Dopamine antagonist; Serotonin antagonist; Butyrophenone derivatives; Developmental disorder; Serotonine receptor; Haloperidol; Autism; D2 Dopamine receptor; Treatment; Adolescent; Double blind study; Risperidone; Child; Benzisoxazole derivatives; Comparative study

Objective The aim of the study was to compare safety, efficacy and tolerability of risperidone with haloperidol in the treatment of Autistic Disorder (AD). Method This study was designed as a double-blind, prospective, for a 12-week period. A total of 30 subjects, between the ages of 8 and 18 with A...