Impact of Penicillin Allergy on Time to First Dose of Antimicrobial Therapy and Clinical Outcomes

• Published in: Clinical therapeutics Vol. 39; no. 11; pp. 2276 - 2283
• Main Authors: Conway, Erin L., Lin, Ken, Sellick, John A., Kurtzhalts, Kari, Carbo, James, Ott, Michael C., Mergenhagen, Kari A.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.11.2017; Elsevier Limited
• Subjects: Aged; Aged, 80 and over; Allergies; allergy; Anti-Bacterial Agents - administration & dosage; Anti-Bacterial Agents - adverse effects; Anti-Bacterial Agents - therapeutic use; Antibiotics; Antimicrobial agents; Bacteremia - drug therapy; Carbapenems - therapeutic use; Clinical outcomes; Comorbidity; Drug Hypersensitivity - diagnosis; emergency department; Emergency Service, Hospital; Female; Health care policy; Hospitalization; Hospitals; Humans; Male; Middle Aged; Mortality; Patient Readmission; Patients; Penicillin; Penicillins - adverse effects; Pneumonia; Pneumonia - drug therapy; Prospective payment systems; Retrospective Studies; Sepsis; Sepsis - drug therapy; Studies; Systematic review; Therapy; Urinary tract infections; Urinary Tract Infections - drug therapy; Ventilators; Veterans; penicillin; emergency department; allergy

The objective of this study was to evaluate the impact of a listed penicillin allergy on the time to first dose of antibiotic in a Veterans Affairs hospital. Additional clinical outcomes of patients with penicillin allergies were compared with those of patients without a penicillin allergy. A retros...