Poly-isoprenylated ifosfamide analogs: Preactivated antitumor agents as free formulation or nanoassemblies - Skarbek, Charles; Delahousse, Julia; Pioche-Durieu, Catherine; Baconnais, Sonia; Deroussent, Alain; Renevret, Patrice; Rivard, Michael; Desmaele, Didier; Martens, Thierry; Le Cam, Eric; Couvreur, Patrick; Paci, Angelo (International journal of pharmaceutics, 2017)
Keywords: Animals; Antineoplastic Agents, Alkylating - administration & dosage; Antineoplastic Agents, Alkylating - pharmacokinetics; Cancer drug delivery; Cell Line, Tumor; Cell Survival - drug effects; Humans; Ifosfamide; Ifosfamide - administration & dosage; Ifosfamide - analogs & derivatives; Ifosfamide - chemistry; Ifosfamide - pharmacokinetics; Life Sciences; Male; Maximum Tolerated Dose; Mice, Nude; Nanoassemblies; Nanostructures - administration & dosage; Nanostructures - chemistry; Prenylation; Prodrug; FF; NAs; CAA; DMSO; Ifosfamide; Nanoassemblies; EPR; IP; Prodrug; IV; LC–MS/MS; AUC; Cancer drug delivery; DDS; IFO; NA; PdI; DNA; MTD; TEM