Progress in brain cannabinoid CB2 receptor research: From genes to behavior

• Published in: Neuroscience and biobehavioral reviews Vol. 98; pp. 208 - 220
• Main Authors: Jordan, Chloe J., Xi, Zheng-Xiong
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.03.2019
• Subjects: Brain CB2 receptors; Cannabinoids; deltaΔ9-THC9; Neuronal CB2 receptors; VTA dopamine neurons; Brain CB2 receptors; Cannabinoids; deltaΔ9-THC9; VTA dopamine neurons; Neuronal CB2 receptors
• ISSN: 0149-7634; 1873-7528; 1873-7528
• DOI: 10.1016/j.neubiorev.2018.12.026

•Cannabinoid CB2R was initially assumed to be exclusively in the periphery.•Technological innovations have revealed functional CB2R expression in neurons.•Species differences exist in CB2R genes, receptor expression, and function.•Region-specific CB2R transcripts are found in the brain and periphery...