Successful allogeneic hematopoietic stem cell transplantation in a patient with type I CD36 deficiency: a case study and literature review

• Published in: International journal of hematology Vol. 118; no. 5; pp. 656 - 660
• Main Authors: Okuyama, Shuhei, Sumi, Masahiko, Ishikawa, Ryuto, Shishido, Tsutomu, Koyama, Daisuke, Ueki, Toshimitsu, Takahashi, Daisuke, Kobayashi, Hironori, Kobayashi, Hikaru, Tsuno, Nelson Hirokazu
• Format: Journal Article
• Language: English
• Published: Singapore Springer Nature Singapore 01.11.2023; Springer Nature B.V
• Subjects: Acute myeloid leukemia; Antibodies; Antigens; Blood platelets; Blood transfusion; Bone marrow transplantation; Case Report; CD36 antigen; Chemotherapy; Complications; Hematology; Hematopoietic stem cells; Histocompatibility antigen HLA; Leukemia; Literature reviews; Medicine; Medicine & Public Health; Monocytes; Oncology; Patients; Peripheral blood; Platelets; Remission; Stem cell transplantation; Stem cells; Thermal resistance; Transfusion; Transplantation; CD36 deficiency; Platelet transfusion refractoriness; Patient blood management; Anti-CD36; Hematopoietic stem cell

Background CD36-deficient individuals may produce anti-CD36 antibodies through antigenic exposure to CD36, in situations including blood transfusions. Therefore, allogeneic hematopoietic stem cell transplantation (HSCT) from CD36-positive donors to CD36-negative patients remains a challenge. Case re...