TrkB promotes laryngeal cancer metastasis via activation PI3K/AKT pathway

• Published in: Oncotarget Vol. 8; no. 65; pp. 108726 - 108737
• Main Authors: Jiang, Liang, Wang, Zhihai, Liu, Chuan, Gong, Zhitao, Yang, Yucheng, Kang, Houyong, Li, Yanshi, Hu, Guohua
• Format: Journal Article
• Language: English
• Published: United States Impact Journals LLC 12.12.2017
• Subjects: Research Paper; TrkB; laryngeal cancer; tumorigenicity; PI3K/AKT pathway

The aim of our study was to investigate the role of TrkB pathway in tumor occurrence and development for in order to provide theoretical basis to laryngeal cancer therapy. Biological characteristics of the cells were studied by migration tests and colony forming assay. Gene and protein expression an...