Tumor biology experimental course design based on the integration of molecular biology and metabolomics

• Published in: Cogent education Vol. 11; no. 1
• Main Authors: Zhu, Xinliang, Tang, Ting
• Format: Journal Article
• Language: English
• Published: Abingdon Cogent 31.12.2024; Taylor & Francis Ltd; Taylor & Francis Group
• Subjects: Biochemistry; Bioinformatics; Biological Sciences; Biology; Classroom Practice; College Science; Comprehensive experimental course; Course Content; Course Objectives; Curricula; Curriculum Development; Data Analysis; Database Design; Database Management Systems; Educational Change; Educational Technology; Experimental Curriculum; Experimental Teaching; Genetics; Graduation Requirements; Higher Education; Independent Study; Influence of Technology; metabolomics; Molecular biology; Oncology; Outcome Based Education; Problem Based Learning; Research Design; Science Education; Science Instruction; Scientific Research; Study Skills; Tumors
• ISSN: 2331-186X; 2331-186X
• DOI: 10.1080/2331186X.2024.2381876

In recent years, single-subject experimental courses have not been able to meet the demands of the comprehensive development of life sciences. This study is based on two fundamental disciplines, molecular biology and metabolomics, with the analysis and intervention of tumor-related genes as the starting point. A comprehensive experimental course has been set up to analyze oncological genetic abnormal induced molecular signature and metabolome feature alterations through in vitro and in vivo experimental validations. This newly designed course combines guide theories and practical instructions. Through database screening, in vitro research and in vivo research, student's research interest and knowledge reserves are greatly enhanced and a foundation is laid for further scientific research in the future.