Relative fracture risk in patients with diabetes mellitus, and the impact of insulin and oral antidiabetic medication on relative fracture risk

• Published in: Diabetologia Vol. 48; no. 7; pp. 1292 - 1299
• Main Authors: Vestergaard, P., Rejnmark, L., Mosekilde, L.
• Format: Journal Article
• Language: English
• Published: Berlin Springer 01.07.2005; Springer Nature B.V
• Subjects: Administration, Oral; Adult; Antidiabetics; Biological and medical sciences; Bone density; Case-Control Studies; Diabetes; Diabetes Complications - epidemiology; Diabetes Mellitus, Type 1 - classification; Diabetes Mellitus, Type 1 - drug therapy; Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - drug therapy; Diabetes. Impaired glucose tolerance; Disease; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Female; Fractures; Fractures, Bone - epidemiology; Fractures, Bone - etiology; Hip joint; Humans; Hypoglycemic Agents - administration & dosage; Hypoglycemic Agents - therapeutic use; Insulin - therapeutic use; Insulin resistance; Male; Medical sciences; Metabolism; Reference Values; Risk; Scandals; Denmark; Aarhus Denmark; Endocrinopathy; Human; Pancreatic hormone; Sulphonylurea; Diabetes mellitus; Diseases of the osteoarticular system; Risk; Fracture; Trauma; Insulin; Epidemiology; Risk factor; Diabetes; Metformin

We studied the association between fractures and type 1 and type 2 diabetes mellitus. In this case-control study, all subjects diagnosed with a fracture (n=124,655) in Denmark served as cases, and for each case three control subjects (n=373,962) matched for sex and age were retrieved from the genera...