Artesunate activates the ATF4-CHOP-CHAC1 pathway and affects ferroptosis in Burkitt's Lymphoma

• Published in: Biochemical and biophysical research communications Vol. 519; no. 3; pp. 533 - 539
• Main Authors: Wang, Ning, Zeng, Guang-Zhi, Yin, Jun-Lin, Bian, Zhao-Xiang
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 12.11.2019
• Subjects: Artesunate; Burkitt's lymphoma; CHAC1; Ferroptosis; Xenograft; Ferroptosis; Xenograft; CHAC1; Artesunate; Burkitt's lymphoma

Currently, there is no effective treatment for Burkitt's lymphoma in patients aged above 60 years, and thus research on effective treatment options for Burkitt's lymphoma has been gaining increasing attention. Artesunate has been identified as a novel effective growth suppressor in Burkitt...