Possible gatifloxacin-induced fulminant hepatic failure

• Published in: The Annals of pharmacotherapy Vol. 36; no. 7-8; p. 1162
• Main Authors: Coleman, Craig I, Spencer, Jeffrey V, Chung, Jenny O, Reddy, Prabashni
• Format: Journal Article
• Language: English
• Published: United States 01.07.2002
• Subjects: Aged; Anti-Infective Agents - adverse effects; Fatal Outcome; Fluoroquinolones; Humans; Liver Failure - chemically induced; Liver Function Tests; Male

To report a case of fulminant hepatic failure associated with the use of gatifloxacin. A 76-year-old white man was found to have an approximate 1-week history of worsening jaundice on the last day of a 10-day course of gatifloxacin for treatment of impetigo while at his skilled nursing facility. Liv...