Comparison of MicroRNA Expression in Tears of Normal Subjects and Sjögren Syndrome Patients

• Published in: Investigative ophthalmology & visual science Vol. 60; no. 14; p. 4889
• Main Authors: Kim, Yu Jeong, Yeon, Yeji, Lee, Won June, Shin, Yong Un, Cho, Heeyoon, Sung, Yoon-Kyoung, Kim, Du Roo, Lim, Han Woong, Kang, Min Ho
• Format: Journal Article
• Language: English
• Published: United States 01.11.2019
• Subjects: Adult; DNA, Complementary - genetics; Female; Gene Expression Regulation - physiology; Healthy Volunteers; Humans; Male; MicroRNAs - genetics; Middle Aged; Real-Time Polymerase Chain Reaction; Sjogren's Syndrome - metabolism; Tears - metabolism

Deregulated expression of several microRNAs (miRNAs) in sera or salivary glands of patients with Sjögren syndrome (SS) has been reported. However, none have investigated miRNAs in samples that can represent lacrimal glands. We compared the miRNAs expression in the tears of SS patients and healthy co...