Interlaboratory standardization of glycated hemoglobin determinations

• Published in: Clinical chemistry (Baltimore, Md.) Vol. 32; no. 2; pp. 358 - 360
• Main Authors: Little, RR, England, JD, Wiedmeyer, HM, McKenzie, EM, Mitra, R, Erhart, PM, Durham, JB, Goldstein, DE
• Format: Journal Article
• Language: English
• Published: Washington, DC Am Assoc Clin Chem 01.02.1986; American Association for Clinical Chemistry
• Subjects: Analytical, structural and metabolic biochemistry; Biological and medical sciences; Chromatography, Affinity; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Diabetes Mellitus - blood; Fundamental and applied biological sciences. Psychology; Glycated Hemoglobin A - analysis; Glycated Hemoglobin A - standards; Hemoproteins; Humans; Laboratories - organization & administration; Laboratories - standards; Metalloproteins; Proteins; Quality Control; Reference Standards; Assay; Human; Hemoprotein; Clinical biology; Quality control; Standardization; Hemoglobin; Hemoglobin A1; Chromatography; Blood

As the clinical utility of glycated hemoglobin (gHb) measurement increases, so does the need for standardization of values between different methods and different laboratories. Using three different methods, we examined the feasibility of interlaboratory standardization of gHb measurement. A liquid-...