Impact of the Presenting Symptom on Time Intervals and Diagnostic Routes of Patients with Symptomatic Oral Cancer
This investigation was aimed at determining the time intervals from the presenting symptoms until the beginning of oral cancer treatment and their relative contribution to the total time, and to assess the impact of the presenting symptom on diagnostic timelines and patient referral routes. A cross-...
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Published in | Cancers Vol. 13; no. 20; p. 5163 |
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Abstract | This investigation was aimed at determining the time intervals from the presenting symptoms until the beginning of oral cancer treatment and their relative contribution to the total time, and to assess the impact of the presenting symptom on diagnostic timelines and patient referral routes. A cross-sectional, ambispective study was designed to investigate symptomatic incident cases. The Aarhus statement was used as a conceptual framework. Strategies for minimizing potential recall biases were implemented. A sample of 181 patients was recruited (power: 99.5%; α = 0.05). The patient interval reached 58.2 days (95% CI, 40.3–76.2), which accounted for 74% of the whole prereferral interval and for more than one third of the total time interval. The presenting symptom (trigger for consultation) influenced both the number of primary care consultations and the length of time to diagnosis. General dental practitioners generated longer intervals to diagnosis (p < 0.005) and needed more consultations before referring a patient (RR = 0.76; 95% CI, 0.61–0.93), than general medical practitioners. The current study identifies the patient as the main target for interventions to improve awareness and reinforces the need for increased alertness amongst healthcare professionals about presenting symptoms of oral cancer and to diminish the number of prereferral consultations in order to optimize the primary care interval. |
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AbstractList | This investigation was aimed at determining the time intervals from the presenting symptoms until the beginning of oral cancer treatment and their relative contribution to the total time, and to assess the impact of the presenting symptom on diagnostic timelines and patient referral routes. A cross-sectional, ambispective study was designed to investigate symptomatic incident cases. The Aarhus statement was used as a conceptual framework. Strategies for minimizing potential recall biases were implemented. A sample of 181 patients was recruited (power: 99.5%; α = 0.05). The patient interval reached 58.2 days (95% CI, 40.3–76.2), which accounted for 74% of the whole prereferral interval and for more than one third of the total time interval. The presenting symptom (trigger for consultation) influenced both the number of primary care consultations and the length of time to diagnosis. General dental practitioners generated longer intervals to diagnosis (p < 0.005) and needed more consultations before referring a patient (RR = 0.76; 95% CI, 0.61–0.93), than general medical practitioners. The current study identifies the patient as the main target for interventions to improve awareness and reinforces the need for increased alertness amongst healthcare professionals about presenting symptoms of oral cancer and to diminish the number of prereferral consultations in order to optimize the primary care interval. Simple SummaryInformation about the relative length of patient stays, primary care, and prereferral intervals (from symptom onset to specialist referral) is very scarce, and how the presenting symptoms influence these intervals and referral routes remains unknown. This study assesses the impact of presenting symptoms on time intervals, number of visits at the primary care level, and referral pattern of patients with symptomatic oral cancer. This approach will allow targets to be identified for future interventions and the optimization of the treatment pathway for symptomatic oral cancer patients.AbstractThis investigation was aimed at determining the time intervals from the presenting symptoms until the beginning of oral cancer treatment and their relative contribution to the total time, and to assess the impact of the presenting symptom on diagnostic timelines and patient referral routes. A cross-sectional, ambispective study was designed to investigate symptomatic incident cases. The Aarhus statement was used as a conceptual framework. Strategies for minimizing potential recall biases were implemented. A sample of 181 patients was recruited (power: 99.5%; α = 0.05). The patient interval reached 58.2 days (95% CI, 40.3–76.2), which accounted for 74% of the whole prereferral interval and for more than one third of the total time interval. The presenting symptom (trigger for consultation) influenced both the number of primary care consultations and the length of time to diagnosis. General dental practitioners generated longer intervals to diagnosis (p < 0.005) and needed more consultations before referring a patient (RR = 0.76; 95% CI, 0.61–0.93), than general medical practitioners. The current study identifies the patient as the main target for interventions to improve awareness and reinforces the need for increased alertness amongst healthcare professionals about presenting symptoms of oral cancer and to diminish the number of prereferral consultations in order to optimize the primary care interval. |
Author | García-Rozado, Álvaro Varela-Centelles, Pablo Ignacio Baz, Pablo Castelo López, Daniel Pérez Romero-Méndez, Amparo Seoane, Juan López-Cedrún, José Luis |
AuthorAffiliation | 1 Department of Surgery and Medical-Surgical Specialities, Medical & Dental School, University of Santiago de Compostela, Entrerríos s/n, 15705 Santiago de Compostela, Spain; pabloignacio.varela@usc.es (P.I.V.-C.); daniel.perez.lopez@rai.usc.es (D.P.L.); pablo.castelo.baz@usc.es (P.C.B.); mariaamparo.romero@usc.es (A.R.-M.) 2 Service of Oral and Maxillofacial Surgery, A Coruña University Hospital (CHUAC), Xubias-84, 15006 A Coruña, Spain; jose.lopez.cedrun@sergas.es (J.L.L.-C.); Alvaro.Garcia-Rozado.Gonzalez@sergas.es (Á.G.-R.) |
AuthorAffiliation_xml | – name: 2 Service of Oral and Maxillofacial Surgery, A Coruña University Hospital (CHUAC), Xubias-84, 15006 A Coruña, Spain; jose.lopez.cedrun@sergas.es (J.L.L.-C.); Alvaro.Garcia-Rozado.Gonzalez@sergas.es (Á.G.-R.) – name: 1 Department of Surgery and Medical-Surgical Specialities, Medical & Dental School, University of Santiago de Compostela, Entrerríos s/n, 15705 Santiago de Compostela, Spain; pabloignacio.varela@usc.es (P.I.V.-C.); daniel.perez.lopez@rai.usc.es (D.P.L.); pablo.castelo.baz@usc.es (P.C.B.); mariaamparo.romero@usc.es (A.R.-M.) |
Author_xml | – sequence: 1 givenname: Pablo Ignacio surname: Varela-Centelles fullname: Varela-Centelles, Pablo Ignacio – sequence: 2 givenname: Daniel Pérez surname: López fullname: López, Daniel Pérez – sequence: 3 givenname: José Luis surname: López-Cedrún fullname: López-Cedrún, José Luis – sequence: 4 givenname: Álvaro surname: García-Rozado fullname: García-Rozado, Álvaro – sequence: 5 givenname: Pablo Castelo surname: Baz fullname: Baz, Pablo Castelo – sequence: 6 givenname: Amparo surname: Romero-Méndez fullname: Romero-Méndez, Amparo – sequence: 7 givenname: Juan orcidid: 0000-0003-4751-591X surname: Seoane fullname: Seoane, Juan |
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Snippet | This investigation was aimed at determining the time intervals from the presenting symptoms until the beginning of oral cancer treatment and their relative... Simple SummaryInformation about the relative length of patient stays, primary care, and prereferral intervals (from symptom onset to specialist referral) is... |
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SubjectTerms | Confidence intervals Diagnosis Generalized linear models Health services Hospitals Medical diagnosis Mortality Oral cancer Patients Primary care Questionnaires Statistical analysis Tumors Variables |
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Title | Impact of the Presenting Symptom on Time Intervals and Diagnostic Routes of Patients with Symptomatic Oral Cancer |
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