Balanced crystalloid compared with balanced colloid solution using a goal-directed haemodynamic algorithm

• Published in: British journal of anaesthesia : BJA Vol. 110; no. 2; pp. 231 - 240
• Main Authors: Feldheiser, A., Pavlova, V., Bonomo, T., Jones, A., Fotopoulou, C., Sehouli, J., Wernecke, K.-D., Spies, C.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.02.2013; Oxford University Press
• Subjects: Algorithms; balanced starch solution; Blood Pressure - drug effects; Blood Pressure - physiology; Cardiotonic Agents - therapeutic use; Double-Blind Method; Endpoint Determination; Fluid Therapy; goal-directed therapy; haemodynamic monitoring; Hemodynamics - drug effects; Hemodynamics - physiology; Humans; Hydroxyethyl Starch Derivatives - therapeutic use; Intraoperative Period; Isotonic Solutions - therapeutic use; Length of Stay; ovarian cancer; Patient Selection; Perfusion; Pharmaceutical Solutions; Pilot Projects; Plasma Substitutes - therapeutic use; renal function; Stroke Volume - drug effects; Stroke Volume - physiology; transfusion; Vasoconstrictor Agents - therapeutic use; renal function; goal-directed therapy; transfusion; balanced starch solution; haemodynamic monitoring; ovarian cancer

Controversy exists regarding the optimal i.v. fluids for use with a goal-directed haemodynamic algorithm. In a double-blind pilot study, we randomly assigned 50 patients with primary ovarian cancer undergoing cytoreductive surgery to receive either balanced crystalloid or balanced starch (HES, 130/0...