Volatile anaesthetics and positive pressure ventilation reduce left atrial performance: a transthoracic echocardiographic study in young healthy adults

• Published in: British journal of anaesthesia : BJA Vol. 112; no. 6; pp. 1032 - 1041
• Main Authors: Freiermuth, D., Skarvan, K., Filipovic, M., Seeberger, M.D., Bolliger, D.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.06.2014; Oxford University Press
• Subjects: Adolescent; Adult; anaesthetic effects; Anesthesia, General - methods; Anesthetics, Inhalation - adverse effects; echocardiography, transthoracic; Female; Healthy Volunteers; Heart Atria - diagnostic imaging; Heart Atria - drug effects; Humans; inhalation anaesthetics; Isoflurane - adverse effects; Isoflurane - analogs & derivatives; Laryngeal Masks; left atrial function; Male; Methyl Ethers - adverse effects; Middle Aged; Positive-Pressure Respiration - methods; Reference Values; Ultrasonography; Young Adult; inhalation anaesthetics; echocardiography, transthoracic; left atrial function; anaesthetic effects

Animal and in vitro studies suggest that volatile anaesthetics affect left atrial (LA) performance. We hypothesized that human LA pump function and dimensions are altered by volatile anaesthetics in vivo. We performed transthoracic echocardiographic (TTE) measurements in 59 healthy subjects (aged 18...