Determination of inosine 5′-monophosphate dehydrogenase activity in red blood cells of thiopurine-treated patients using HPLC - Beringer, Audrey; Citterio-Quentin, Antony; Otero, Rebeca Obenza; Gustin, Clémence; Clarke, Rebecca; Salvi, Jean-Paul; Boulieu, Roselyne (Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2017)
Keywords: Adolescent; Adult; adults; Aged; anion exchange; Child; Child, Preschool; Chromatography, High Pressure Liquid - methods; disease control; drugs; erythrocytes; Erythrocytes - enzymology; Erythrocytes - metabolism; Female; genetic variation; graft rejection; high performance liquid chromatography; Humans; hydrophobicity; IMP Dehydrogenase - analysis; IMP Dehydrogenase - metabolism; IMPDH; inosine monophosphate; Inosine monophosphate dehydrogenase; Linear Models; Male; metabolism; Middle Aged; patients; Phenotype; Purines - analysis; Purines - metabolism; Red blood cells; Reproducibility of Results; Ribonucleotides - analysis; Ribonucleotides - metabolism; therapeutics; thiopurine S-methyltransferase; Thiopurines; Young Adult; Inosine monophosphate dehydrogenase; 6-MP; TPMT; DTT; meTIMP; RBCs; AZA; 6-TGN; IBD; Thiopurines; IMP; Phenotype; Red blood cells; IMPDH; 6-MeMPN; XMP; β-NAD; ITPA; MPA