Risk of Malignant Transformation in 3173 Subjects with Histopathologically Confirmed Oral Lichen Planus: A 33-Year Cohort Study in Northern Italy

• Published in: Cancers Vol. 13; no. 22; p. 5740
• Main Authors: Arduino, Paolo G., Magliano, Alessandro, Gambino, Alessio, Macciotta, Alessandra, Carbone, Mario, Conrotto, Davide, Karimi, Dora, Carrozzo, Marco, Broccoletti, Roberto
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 16.11.2021; MDPI
• Subjects: Antigens; Cohort analysis; Diagnosis; Hepatitis C; Lichen planus; Oral cancer; Oral carcinoma; Oral squamous cell carcinoma; Patients; Population studies; Radiation therapy; Surgery; Italy

Background: Oral lichen planus (OLP) is considered an oral potentially malignant disorder. The aim of our study was to estimate the risk for oral cancer in patients diagnosed with OLP. Methods: A population-based cohort study between January 1988 and December 2020 at one hospital in Northern Italy w...