Imaging gastrointestinal damage due to acute mercury poisoning using a mitochondria-targeted dual near-infrared fluorescent probe

• Published in: Journal of hazardous materials Vol. 470; p. 134269
• Main Authors: Zhou, Jianjian, Li, Jianchun, Xu, Xiaotong, Long, Shi, Cui, Ningning, Zhang, Yong, Shi, Lihong, Zhou, Jin
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 15.05.2024
• Subjects: Acute mercury poisoning; Animals; brain; death; diarrhea; diet; distress; Female; fluorescence; fluorescent dyes; Fluorescent Dyes - chemistry; Gastrointestinal Diseases - chemically induced; Gastrointestinal Diseases - diagnostic imaging; gastrointestinal system; Gastrointestinal Tract - diagnostic imaging; Gastrointestinal Tract - drug effects; Gastrointestinal Tract - metabolism; gingivitis; Hazardous; HeLa Cells; Humans; inflammation; mercury; Mercury - toxicity; Mercury ion; Mercury Poisoning - diagnostic imaging; Mice; mitochondria; Mitochondria - drug effects; Near-infrared (NIR) fluorescence; neurodevelopment; Optical Imaging; people; public health; rhodamines; Rhodamines - chemistry; Rhodamines - toxicity; species; thiolactones; Mercury ion; Near-infrared (NIR) fluorescence; Hazardous; Acute mercury poisoning

Mercury (Hg) is one of the most widespread pollutants that pose serious threats to public health and the environment. People are inevitably exposed to Hg via different routes, such as respiration, dermal contact, drinking or diet. Hg poisoning could cause gingivitis, inflammation, vomiting and diarr...