Continuous intravesical lidocaine treatment for interstitial cystitis/bladder pain syndrome: safety and efficacy of a new drug delivery device

• Published in: Science translational medicine Vol. 4; no. 143; p. 143ra100
• Main Authors: Nickel, J Curtis, Jain, Pankaj, Shore, Neal, Anderson, Jessica, Giesing, Dennis, Lee, Heejin, Kim, Grace, Daniel, Karen, White, Suellen, Larrivee-Elkins, Cheryl, Lekstrom-Himes, Julie, Cima, Michael
• Format: Journal Article
• Language: English
• Published: United States 18.07.2012
• Subjects: Administration, Intravesical; Adult; Cystitis, Interstitial - drug therapy; Female; Humans; Lidocaine - administration & dosage; Lidocaine - adverse effects; Lidocaine - therapeutic use; Middle Aged; Treatment Outcome; Young Adult

Limited treatment options exist for patients who suffer from a painful bladder condition known as interstitial cystitis/bladder pain syndrome (IC/BPS). Whether given systemically (orally) or by short-duration (1 to 2 hours) exposure via intravesical instillation, therapeutic agents have exhibited po...