Eicosapentaenoic acid promotes mitochondrial biogenesis and beige-like features in subcutaneous adipocytes from overweight subjects - Laiglesia, L.M.; Lorente-Cebrián, S.; Prieto-Hontoria, P.L.; Fernández-Galilea, M.; Ribeiro, S.M.R.; Sáinz, N.; Martínez, J.A.; Moreno-Aliaga, M.J. (The Journal of nutritional biochemistry, 2016)
Keywords: Acyl-CoA Oxidase - chemistry; Acyl-CoA Oxidase - genetics; Acyl-CoA Oxidase - metabolism; adipocytes; Adipocytes, Beige - enzymology; Adipocytes, Beige - metabolism; Adipocytes, Beige - pathology; Adipocytes, White - enzymology; Adipocytes, White - metabolism; Adipocytes, White - pathology; Adipogenesis; AMP-activated protein kinase; beta oxidation; biogenesis; Biomarkers - metabolism; Body Mass Index; Browning; Carnitine O-Palmitoyltransferase - chemistry; Carnitine O-Palmitoyltransferase - genetics; Carnitine O-Palmitoyltransferase - metabolism; Cells, Cultured; cytochrome-c oxidase; Diacylglycerol O-Acyltransferase - antagonists & inhibitors; Diacylglycerol O-Acyltransferase - genetics; Diacylglycerol O-Acyltransferase - metabolism; eicosapentaenoic acid; Eicosapentaenoic Acid - metabolism; Energy Metabolism; EPA; Fatty acid oxidation; Fatty Acid Synthases - antagonists & inhibitors; Fatty Acid Synthases - genetics; Fatty Acid Synthases - metabolism; Female; females; gene expression; gene expression regulation; Gene Expression Regulation, Enzymologic; genes; Humans; Lipid Metabolism; Lipogenesis; messenger RNA; metabolic diseases; mitochondria; Mitochondrial biogenesis; Mitochondrial Dynamics; N-3 PUFAs; omega-3 fatty acids; Organelle Biogenesis; Osmolar Concentration; overweight; peroxisome proliferator-activated receptors; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; Stearoyl-CoA Desaturase - antagonists & inhibitors; Stearoyl-CoA Desaturase - genetics; Stearoyl-CoA Desaturase - metabolism; Subcutaneous Fat, Abdominal - enzymology; Subcutaneous Fat, Abdominal - metabolism; Subcutaneous Fat, Abdominal - pathology; Fatty acid oxidation; N-3 PUFAs; Browning; Mitochondrial biogenesis; Lipogenesis; EPA