Water soluble AIEgen-based thermosensitive and antibacterial hydroxypropyl chitin hydrogels for non-invasive visualization and wound healing

• Published in: Carbohydrate polymers Vol. 319; p. 121186
• Main Authors: Huang, Long, Cai, Mingzhen, Qiao, Qianqian, Li, Taotao, Chen, Junyu, Jiang, Xulin
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.11.2023
• Subjects: AIEgen; Anti-Bacterial Agents - pharmacology; antibacterial properties; biocompatibility; biodegradability; body temperature; chemical bonding; chitin; Chitin - pharmacology; fluorescence; Fluorescence imaging; Hydrogels; Hydrogels - pharmacology; irradiation; quaternary ammonium compounds; reactive oxygen species; Reactive Oxygen Species - pharmacology; solar radiation; Sunlight-triggered; Synergetic antibacterial; thermosensitivity; Water; water solubility; Wound Healing; AIEgen; Fluorescence imaging; Hydrogels; 4-(Diphenylamino) Benzaldehyde (PubChem CID: 77846); Trifluoroacetic acid (PubChem CID: 6422); Piperidine (PubChem CID: 8082); Sunlight-triggered; Sodium hydroxide (PubChem CID: 14798); Urea (PubChem CID: 1176); Propylene oxide (PubChem CID: 6378); 4-Picoline (PubChem CID: 7963); Synergetic antibacterial; Chitin (PubChem CID: 6857375); tert-Butyl (3-bromopropyl) carbamate (PubChem CID: 4460490)

Antimicrobial hydrogels containing antibacterial agents have been extensively studied for postoperative infections, wound repair and tissue engineering. However, the abuse of antibiotics has led to the enhancement of bacterial resistance and traditional antibacterial agents are losing their effect....