A mitotically unstable human dicentric Y chromosome in a male pseudohermaphrodite

• Published in: Cytogenetics and cell genetics Vol. 17; no. 1; p. 42
• Main Authors: Buchanan, P D, Wyandt, H E, D'Ercole, A J, Rao, K W, Hartsell, M L
• Format: Journal Article
• Language: English
• Published: Switzerland 1976
• Subjects: Cell Line; Child, Preschool; Disorders of Sex Development - genetics; Humans; Infant, Newborn; Male; Mitosis; Sex Chromatin; Sex Chromosomes

A patient with a mitotically unstable dic(Y)(p11) chromosome is reported. Physical examination revealed a small penis with severe hypospadia, undescended testes, rudimetary vagina, uterus, left fallopian tube, and no stigmata of Turner syndrome. Longitudinal chromosome studies over a four-year perio...