Association between syndecan-4 and subclinical atherosclerosis in ankylosing spondylitis

• Published in: Medicine (Baltimore) Vol. 103; no. 3; p. e37019
• Main Authors: Sertdemir, Ahmet L., Şahin, Ahmet T., Duran, Mustafa, Çelik, Mustafa, Tatar, Sefa, Oktay, İrem, Alsancak, Yakup
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 19.01.2024
• Subjects: Atherosclerosis - epidemiology; Carotid Intima-Media Thickness; Humans; Linear Models; Risk Factors; Spondylitis, Ankylosing - complications; Syndecan-4; subclinical atherosclerosis; syndecan-4; ankylosing spondylitis
• ISSN: 0025-7974; 1536-5964; 1536-5964
• DOI: 10.1097/MD.0000000000037019

Background: Despite advances in the diagnosis and treatment of ankylosing spondylitis (AS), the risk of cardiovascular complications in AS patients is still higher than in the general population. Macrophages are at the intersection of the basic pathogenetic processes of AS and atherosclerosis. Altho...