Experiences of Two Centers in Percutaneous Ventricular Septal Defect Closure Using Konar Multifunctional Occluder

• Published in: Anatolian journal of cardiology Vol. 26; no. 4; pp. 276 - 285
• Main Authors: Kamalı, Hacer, Sivaslı Gül, Özlem, Çoban, Şenay, Sarı, Gizem, Sarıtaş, Türkay, Erdem, Abdullah, Aldudak, Bedri
• Format: Journal Article
• Language: English
• Published: Turkey Turkish Society of Cardiology 01.04.2022; KARE Publishing
• Subjects: atrioventricular block; Atrioventricular Block - therapy; Cardiac Catheterization; Heart Septal Defects, Ventricular - diagnostic imaging; Heart Septal Defects, Ventricular - surgery; Humans; Infant; konar-mf (multifunc-tional occluder); Original Investigation; percutaneous vsd closure; Retrospective Studies; Septal Occluder Device; Treatment Outcome
• DOI: 10.5152/AnatolJCardiol.2021.464
• ISSN: 2149-2263

Transcatheter closure of perimembraneous ventricular septal defect still poses a challenge due to the adjacent structures of the tricuspid and aortic valves and the risk of atrioventricular block. We report our experience at 2 centers using the KONAR-MF (multifunctional occluder) ventricular septal defect device, which gained its CE mark in May 2018. A retrospective study was carried out on all patients who underwent transcatheter ventricular septal defect closure with the KONAR-MF (multifunctional occluder) ventricular septal defect device at 2 centers. A total of 47 patients were identified. The median age and weight of the patients were 25.8 months and 11 kg. The ventricular septal defects that were closed in 5 cases were post-operative hemodynamically significant residual ventricular septal defects. Forty-eight devices were used in the 47 cases. As for the location of the ventricular septal defect, 40/48 (83.33%) ventricular septal defects were perimembranous and 8/48 (16.66%) were muscular. The percutaneous device closure was successful in 46 procedures (95.8%). Device embolization was observed in 2 patients, and a significant residual shunt was observed in 2 cases. In the follow-up, there was no enhancement in the residual shunt in the remaining cases. Temporary atrioventricular block occurred in 2 cases during the procedure and improved after long sheath withdrawal. Soft, flexible, and low-profile KONAR-MF (multifunctional occluder) occluders ensure easy and safe implantation, and small sheath sizes allow for their use in small infants. Although near and mid-term follow-ups did not indicate any permanent atrioventricular block, a larger sample of patients and a longer follow-up period is necessary to understand long-term outcomes.