Inserting ex vivo Fluorescence Confocal Microscopy Perioperatively in Mohs Micrographic Surgery Expedites Bedside Assessment of Excision Margins in Recurrent Basal Cell Carcinoma
Mohs micrographic surgery can be employed in recurrent basal cell carcinoma, although it is a time-consuming technique. Recently, ex vivo fluorescence confocal microscopy (FCM) has been employed to obtain a fast assessment of tumor margins at the bedside. In our case we successfully employed ex vivo...
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| Published in | Dermatology (Basel) Vol. 227; no. 1; pp. 89 - 92 |
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| Main Authors | , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
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Basel, Switzerland
S. Karger AG
01.01.2013
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| Abstract | Mohs micrographic surgery can be employed in recurrent basal cell carcinoma, although it is a time-consuming technique. Recently, ex vivo fluorescence confocal microscopy (FCM) has been employed to obtain a fast assessment of tumor margins at the bedside. In our case we successfully employed ex vivo FCM to assess the tumor margins and we treated the persistent tumor with intensity-modulated radiation therapy. Our case demonstrates that a multidisciplinary approach is very efficient in managing complex and recurrent tumors and highlights the benefits of FCM as a new technique that can be used in the surgical theater to speed up the entire procedure. |
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| AbstractList | Mohs micrographic surgery can be employed in recurrent basal cell carcinoma, although it is a time-consuming technique. Recently, ex vivo fluorescence confocal microscopy (FCM) has been employed to obtain a fast assessment of tumor margins at the bedside. In our case we successfully employed ex vivo FCM to assess the tumor margins and we treated the persistent tumor with intensity-modulated radiation therapy. Our case demonstrates that a multidisciplinary approach is very efficient in managing complex and recurrent tumors and highlights the benefits of FCM as a new technique that can be used in the surgical theater to speed up the entire procedure. © 2013 S. Karger AG, Basel [PUBLICATION ABSTRACT] Mohs micrographic surgery can be employed in recurrent basal cell carcinoma, although it is a time-consuming technique. Recently, ex vivo fluorescence confocal microscopy (FCM) has been employed to obtain a fast assessment of tumor margins at the bedside. In our case we successfully employed ex vivo FCM to assess the tumor margins and we treated the persistent tumor with intensity-modulated radiation therapy. Our case demonstrates that a multidisciplinary approach is very efficient in managing complex and recurrent tumors and highlights the benefits of FCM as a new technique that can be used in the surgical theater to speed up the entire procedure. |
| Author | Piana, Simonetta Castagnetti, Fabio Ragazzi, Moira Palmieri, Tamara Moscarella, Elvira Lallas, Aimilios Zalaudek, Iris Argenziano, Giuseppe Longo, Caterina Gardini, Stefano Pellacani, Giovanni |
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| SubjectTerms | Aged, 80 and over Carcinoma, Basal Cell - pathology Carcinoma, Basal Cell - radiotherapy Carcinoma, Basal Cell - surgery Case Report Fluorescence Humans Male Microscopy Microscopy, Confocal Mohs Surgery - methods Neoplasm Recurrence, Local - pathology Neoplasm Recurrence, Local - radiotherapy Neoplasm Recurrence, Local - surgery Neoplasm, Residual Point-of-Care Systems Radiotherapy, Intensity-Modulated Skin cancer Skin Neoplasms - pathology Skin Neoplasms - radiotherapy Skin Neoplasms - surgery Surgical outcomes Surgical techniques |
| Title | Inserting ex vivo Fluorescence Confocal Microscopy Perioperatively in Mohs Micrographic Surgery Expedites Bedside Assessment of Excision Margins in Recurrent Basal Cell Carcinoma |
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