Transit of solids through the human colon: regional quantification in the unprepared bowel

• Published in: The American journal of physiology Vol. 258; no. 6 Pt 1; p. G856
• Main Authors: Proano, M, Camilleri, M, Phillips, S F, Brown, M L, Thomforde, G M
• Format: Journal Article
• Language: English
• Published: United States 01.06.1990
• Subjects: Adult; Colon - diagnostic imaging; Colon - physiology; Feces - analysis; Female; Gastrointestinal Transit; Humans; Indium Radioisotopes; Male; Muscle, Smooth - diagnostic imaging; Muscle, Smooth - physiology; Radionuclide Imaging; Reference Values; Regression Analysis; Time Factors

We used a noninvasive method to label the solid phase of contents in the unprepared human colon. 111In-labeled Amberlite pellets (0.5-1.8 mm diam) were placed in a gelatin capsule that was then coated with a pH-sensitive polymer (methacrylate). In vitro, the capsules disintegrated in simulated small...