Evolution of Diaphragm Thickness during Mechanical Ventilation. Impact of Inspiratory Effort

• Published in: American journal of respiratory and critical care medicine Vol. 192; no. 9; pp. 1080 - 1088
• Main Authors: Goligher, Ewan C., Fan, Eddy, Herridge, Margaret S., Murray, Alistair, Vorona, Stefannie, Brace, Debbie, Rittayamai, Nuttapol, Lanys, Ashley, Tomlinson, George, Singh, Jeffrey M., Bolz, Steffen-Sebastian, Rubenfeld, Gordon D., Kavanagh, Brian P., Brochard, Laurent J., Ferguson, Niall D.
• Format: Journal Article
• Language: English
• Published: United States American Thoracic Society 01.11.2015
• Subjects: Aged; Critical Illness; Diaphragm - diagnostic imaging; Diaphragm - physiopathology; Female; Humans; Male; Middle Aged; Muscle Contraction - physiology; Muscle Weakness - diagnostic imaging; Respiration; Respiration, Artificial; Ultrasonography; artificial respiration; myotrauma; diaphragm function; disuse atrophy; weaning
• ISSN: 1073-449X; 1535-4970
• DOI: 10.1164/rccm.201503-0620OC

Diaphragm atrophy and dysfunction have been reported in humans during mechanical ventilation, but the prevalence, causes, and functional impact of changes in diaphragm thickness during routine mechanical ventilation for critically ill patients are unknown. To describe the evolution of diaphragm thic...