Cerebral vascular response to moderate blood loss: modification by hypertension

• Published in: Stroke (1970) Vol. 14; no. 5; pp. 765 - 768
• Main Authors: HOLLADAY, F. P, BEAN, J. R, YOUNG, B, TODD, E. P, ROY, M. W
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 01.09.1983
• Subjects: Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Animals; Biological and medical sciences; Blood Flow Velocity; Blood Volume; Cats; Cerebral Hemorrhage - physiopathology; Cerebrovascular Circulation; Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care; Female; Hypertension - chemically induced; Hypotension - etiology; Intensive care medicine; Male; Medical sciences; Phenylephrine; Probability; Regional Blood Flow; Vasodilation; Hypertension; Fissipedia; Carnivora; Vertebrata; Experimental disease; Mammalia; Brain (Vertebrata); Hemodynamics; Hemorrhage

To study the effect of non-hypotensive hemorrhage on cerebral blood flow in normo- and hypertensive states, chloralose anesthetized cats were subjected to graded blood loss (5 ml/kg) every 30 min. Cerebral blood flow was measured using radiolabelled microspheres or H2 clearance. Hypertension was pro...