Effect of Convalescent Plasma Therapy on Viral Shedding and Survival in Patients With Coronavirus Disease 2019

• Published in: The Journal of infectious diseases Vol. 222; no. 1; pp. 38 - 43
• Main Authors: Zeng, Qing-Lei, Yu, Zu-Jiang, Gou, Jian-Jun, Li, Guang-Ming, Ma, Shu-Huan, Zhang, Guo-Fan, Xu, Jiang-Hai, Lin, Wan-Bao, Cui, Guang-Lin, Zhang, Min-Min, Li, Cheng, Wang, Ze-Shuai, Zhang, Zhi-Hao, Liu, Zhang-Suo
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 16.06.2020
• Subjects: Adult; Aged; Antibodies, Viral - therapeutic use; Betacoronavirus - genetics; Blood Donors; China; Coronaviridae; Coronavirus Infections - mortality; Coronavirus Infections - therapy; Coronavirus Infections - virology; Coronaviruses; COVID-19; Critical Illness; Female; Humans; Immunization, Passive - adverse effects; Male; Middle Aged; Pandemics; Plasma; Pneumonia, Viral - mortality; Pneumonia, Viral - therapy; Pneumonia, Viral - virology; Real-Time Polymerase Chain Reaction; Respiratory failure; Retrospective Studies; Ribonucleic acid; RNA; RNA, Viral - genetics; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Survival Rate; Treatment Outcome; Virus Shedding - immunology; China; Fatality; Convalescent plasma therapy; Survival rate; Viral shedding; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Coronavirus disease 2019 (COVID-19)

Abstract Currently, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been reported in almost all countries globally. No effective therapy has been documented for COVID-19, and the role of convalescent plasma therapy is unknown. In the c...