Urokinase therapy in neonates with catheter related central venous thrombosis

• Published in: Thrombosis and haemostasis Vol. 73; no. 2; p. 180
• Main Authors: Wever, M L, Liem, K D, Geven, W B, Tanke, R B
• Format: Journal Article
• Language: English
• Published: Germany 01.02.1995
• Subjects: Case-Control Studies; Catheterization, Central Venous - adverse effects; Humans; Infant; Infant, Newborn; Infusions, Intravenous; Thrombophlebitis - drug therapy; Thrombophlebitis - etiology; Treatment Outcome; Urokinase-Type Plasminogen Activator - adverse effects; Urokinase-Type Plasminogen Activator - therapeutic use

The results of fibrinolytic therapy with urokinase were evaluated in 26 neonates with catheter related central venous thrombosis. Complete thrombolysis could be achieved in 13 patients (50%), partial thrombolysis in 3 patients (12%). No effect was seen in 10 patients (38%). Therapy success was influ...