Transcriptomic analysis reveals Cilostazol's role in ameliorating cardiovascular disease: Inhibition of monocyte-to-macrophage differentiation and reduction of endothelial cell reactive oxygen species production

• Published in: Heliyon Vol. 10; no. 7; p. e29194
• Main Authors: Fan, Chia-Ning, Tsai, Tsung-Neng, Lu, Xin-Jie, Lai, Hsing-Fan, Wang, Chun-Hua, Chiu, Yi-Lin
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 15.04.2024; Elsevier

Cardiovascular diseases (CVDs) are the leading global cause of death, with atherosclerosis as the primary cause. Chronic inflammation, endothelial dysfunction, and the role of molecules like nitric oxide and reactive oxygen species are crucial in this context. Our previous research indicated that ci...