The future of lung transplantation

Lung transplantation has been the last of the solid organs to gain traction as a viable therapeutic option. Due to differing standards of care and the relatively low number of lung transplants performed, it has proven difficult to orchestrate prospective multicenter studies to determine best practic...

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Bibliographic Details
Published inChest Vol. 147; no. 2; p. 309
Main Author Nathan, Steven D
Format Journal Article
LanguageEnglish
Published United States 01.02.2015
Subjects
Allografts
Forecasting
Graft Rejection - epidemiology
Graft Rejection - physiopathology
Humans
Lung Transplantation - trends
Patient Selection
Primary Graft Dysfunction - epidemiology
Tissue Donors - statistics & numerical data
Waiting Lists
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Summary:Lung transplantation has been the last of the solid organs to gain traction as a viable therapeutic option. Due to differing standards of care and the relatively low number of lung transplants performed, it has proven difficult to orchestrate prospective multicenter studies to determine best practice and explore novel therapies. Nonetheless, there have been incremental advances in lung transplantation, including liberalization of criteria for both suitable donor organs as well as acceptable recipients. This has resulted in increasing numbers of procedures being performed, and outcomes have improved despite an expanding cohort of sicker patients undergoing lung transplantation. This review will discuss current trends and future developments with a focus on the most pertinent of the pitfalls that may accompany lung transplantation.
ISSN:1931-3543
DOI:10.1378/chest.14-1748