Calcitonin gene-related peptide monoclonal antibodies and medication-overuse headache: stopping excessive pain medication is still necessary

• Published in: Arquivos de neuro-psiquiatria Vol. 83; no. 9; pp. 1 - 4
• Main Author: Rocha-Filho, Pedro Augusto Sampaio
• Format: Journal Article
• Language: English
• Published: Germany Thieme Revinter Publicações 01.09.2025
• Subjects: Analgesics; Analgesics - adverse effects; Antibodies, Monoclonal - therapeutic use; Calcitonin Gene-Related Peptide - antagonists & inhibitors; Calcitonin Gene-Related Peptide - immunology; Headache; Headache Disorders, Secondary; Headache Disorders, Secondary - chemically induced; Headache Disorders, Secondary - drug therapy; Headache Disorders, Secondary - prevention & control; Humans; Migraine Disorders; Migraine Disorders - drug therapy; Review; Tension-Type Headache; Therapeutics

Medication-overuse headache affects 1 to 2% of the global population and is often associated with chronic migraine. This condition significantly impacts the lives of patients, as well as their families, and it poses a major economic burden due to lost productivity and medical costs. The present narr...