High doses of carbamazepine for refractory partial epilepsy

• Published in: Arquivos de neuro-psiquiatria Vol. 54; no. 1; pp. 42 - 46
• Main Authors: Borges Pereira, C, Otto Heise, C, Cukiert, A
• Format: Journal Article
• Language: English
• Published: Brazil Academia Brasileira de Neurologia - ABNEURO 01.03.1996
• Subjects: Adolescent; Adult; Anticonvulsants - administration & dosage; Carbamazepine - administration & dosage; Epilepsies, Partial - drug therapy; Female; Follow-Up Studies; Humans; Male; Middle Aged; NEUROSCIENCES; PSYCHIATRY; Retrospective Studies; Treatment Outcome; epilepsy; effectiveness; epilepsia; carbamazepina; efeitos colaterais; side effects; eficacia; carbamazepine

Forty-eight patients with partial seizures were analysed during treatment with 1200 mg/d or more of carbamazepine (CBZ). Thirty-three were on monotherapy and fifteen on polytherapy. The other drugs were kept unchanged in the patients on polytherapy. The dose of CBZ was increased if no control was ob...